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新型冠状病毒肺炎与甲状腺疾病

陈紫晗 李乃适 连小兰

陈紫晗, 李乃适, 连小兰. 新型冠状病毒肺炎与甲状腺疾病[J]. 协和医学杂志, 2022, 13(3): 487-492. doi: 10.12290/xhyxzz.2021-0791
引用本文: 陈紫晗, 李乃适, 连小兰. 新型冠状病毒肺炎与甲状腺疾病[J]. 协和医学杂志, 2022, 13(3): 487-492. doi: 10.12290/xhyxzz.2021-0791
CHEN Zihan, LI Naishi, LIAN Xiaolan. Coronavirus Disease 2019 and Thyroid Diseases[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(3): 487-492. doi: 10.12290/xhyxzz.2021-0791
Citation: CHEN Zihan, LI Naishi, LIAN Xiaolan. Coronavirus Disease 2019 and Thyroid Diseases[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(3): 487-492. doi: 10.12290/xhyxzz.2021-0791

新型冠状病毒肺炎与甲状腺疾病

doi: 10.12290/xhyxzz.2021-0791
基金项目: 

中国医学科学院医学与健康科技创新工程 2021-1-I2M-022

详细信息
    通讯作者:

    李乃适, E-mail:lns@medmail.com.cn

  • 中图分类号: R581

Coronavirus Disease 2019 and Thyroid Diseases

Funds: 

CAMS Innovation Fund for Medical Sciences 2021-1-I2M-022

More Information
  • 摘要: 自新型冠状病毒肺炎(coronavirus disease 2019, COVID-19)疫情暴发以来, 出现了若干COVID-19相关甲状腺疾病的报道, 包括亚急性甲状腺炎、自身免疫性甲状腺疾病、非甲状腺疾病综合征以及原因未明的甲状腺功能异常。本综述旨在对COVID-19相关甲状腺疾病的临床特点进行总结, 并探究可能的发生机制。
    作者贡献:李乃适、连小兰负责构思论文;陈紫晗负责查阅文献资料和撰写论文;李乃适、连小兰、陈紫晗负责修订论文。
    利益冲突:所有作者均声明不存在利益冲突
  • 表  1  COVID-19伴发GD的病例特点

    病例 年龄
    (岁)
    性别 前驱时间
    (周)*
    既往GD病史 TSH FT3 FT4 TRAb TPOAb 甲状腺放射性碘摄取率 治疗 参考文献
    病例1 21 2 + NR NR MMI+β-RB Harris等[13]
    病例2 45 8 有,已恢复正常2年 NR + NR NR MMI Jiménez-Blanco等[14]
    病例3 61 4 有,已恢复正常4年 NR + NR MMI Jiménez-Blanco等[14]
    病例4 60 5 有,已恢复正常35年 正常范围 + + MMI+β-RB Mateu-Salat等[15]
    病例5 53 9 + + MMI+β-RB Mateu-Salat等[15]
    *发现SARS-CoV-2感染至确诊GD的时间;NR:文献中未提及;COVID-19:新型冠状病毒肺炎;GD:Graves病;TSH:促甲状腺激素;FT3:游离三碘甲状腺原氨酸;FT4:游离甲状腺素;TRAb:促甲状腺激素受体抗体;TPOAb:抗甲状腺过氧化物酶抗体; MMI: 甲巯咪唑;β-RB:β受体阻滞剂
    下载: 导出CSV
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出版历程
  • 收稿日期:  2021-12-15
  • 录用日期:  2021-12-27
  • 网络出版日期:  2021-12-30
  • 刊出日期:  2022-05-30

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