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乳腺癌根治术诱发对侧上肢原发性淋巴水肿加重一例

刘颖 潘伟人 关竞红 赵沃娃 龙笑

刘颖, 潘伟人, 关竞红, 赵沃娃, 龙笑. 乳腺癌根治术诱发对侧上肢原发性淋巴水肿加重一例[J]. 协和医学杂志, 2022, 13(2): 320-323. doi: 10.12290/xhyxzz.2021-0408
引用本文: 刘颖, 潘伟人, 关竞红, 赵沃娃, 龙笑. 乳腺癌根治术诱发对侧上肢原发性淋巴水肿加重一例[J]. 协和医学杂志, 2022, 13(2): 320-323. doi: 10.12290/xhyxzz.2021-0408
LIU Ying, PAN Weiren, GUAN Jinghong, ZHAO Wowa, LONG Xiao. Aggravated Primary Lymphedema of Contralateral Upper Limb After the Radical Mastectomy: A Case Report[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(2): 320-323. doi: 10.12290/xhyxzz.2021-0408
Citation: LIU Ying, PAN Weiren, GUAN Jinghong, ZHAO Wowa, LONG Xiao. Aggravated Primary Lymphedema of Contralateral Upper Limb After the Radical Mastectomy: A Case Report[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(2): 320-323. doi: 10.12290/xhyxzz.2021-0408

乳腺癌根治术诱发对侧上肢原发性淋巴水肿加重一例

doi: 10.12290/xhyxzz.2021-0408
基金项目: 

中国医学科学院医学与健康科技创新工程 2020-I2M-C&T-B-041

详细信息
    通讯作者:

    龙笑,E-mail: pumch4606@sina.com

  • 中图分类号: R737.9;R493

Aggravated Primary Lymphedema of Contralateral Upper Limb After the Radical Mastectomy: A Case Report

Funds: 

CAMS Innovation Fund for Medical Sciences 2020-I2M-C&T-B-041

More Information
  • 摘要: 淋巴水肿是近年来康复医学领域广泛关注的热点问题, 以手法淋巴引流(manual lymphatic drainage, MLD)为关键技术的淋巴水肿综合消肿治疗正在全国各地迅速开展。本文报道1例由一侧乳腺癌根治手术诱发对侧躯干和上肢原发性淋巴水肿加重的罕见病例, 患者通过MLD治疗获得缓解。通过回顾本病例诊治过程, 可加深对淋巴水肿发病机制复杂性的认识, 并为临床个体化诊疗提供借鉴。
    作者贡献:刘颖负责病例诊治及论文撰写;潘伟人负责病例分析、论文修改并提供文献资料;关竞红负责乳腺癌的临床诊断和评估;赵沃娃协助查阅文献资料;龙笑负责淋巴水肿的诊断、病例分析及论文修改。
    利益冲突:所有作者均声明不存在利益冲突
    注:本研究已通过北京协和医院伦理委员会审批(审批号:S-K1885)。
  • 图  1  患者站立位躯干及上肢外观

    A.躯干和上肢前面观:左乳房缺如(术后),右侧胸部、右上肢及右手肿胀,左上肢无明显异常;B.躯干和上肢后面观:右侧背部、右上肢肿胀,左侧背部、左上肢无明显异常

    图  2  两侧乳腺区域之间的外部连接[11]

  • [1] Liu N, Gao M, Yu Z. Dysfunction of dermal initial lymphatics of the arm and upper body quadrant causes congenital arm lymphedema[J]. J Vasc Surg Venous Lymphat Disord, 2021, 9: 482-488. doi:  10.1016/j.jvsv.2020.06.009
    [2] DiSipio T, Rye S, Newman B, et al. Incidence of unilateral arm lymphoedema after breast cancer: A systematic review and meta-analysis[J]. Lancet Oncol, 2013, 14: 500-515. doi:  10.1016/S1470-2045(13)70076-7
    [3] Pain SJ, Barber RW, Ballinger JR, et al. Local vascular access of radioprotein injected subcutaneously in healthy subjects and patients with breast cancer-related lymphedema[J]. J Nucl Med, 2004, 45: 789-796.
    [4] Pain SJ, Purushotham AD, Barber RW, et al. Variation in lymphatic function may predispose to development of breast cancer-related lymphoedema[J]. Eur J Surg Oncol, 2004, 30: 508-514. doi:  10.1016/j.ejso.2004.02.008
    [5] Stanton AW, Modi S, Mellor RH, et al. Recent advances in breast cancer-related lymphedema of the arm: lymphatic pump failure and predisposing factors[J]. Lymphat Res Biol, 2009, 7: 29-45. doi:  10.1089/lrb.2008.1026
    [6] Aldrich MB, Guilliod R, Fife CE, et al. Lymphatic abnormalities in the normal contralateral arms of subjects with breast cancer-related lymphedema as assessed by near-infrared fluorescent imaging[J]. Biomed Opt Express, 2012, 3: 1256-1265. doi:  10.1364/BOE.3.001256
    [7] Bains SK, Peters AM, Zammit C, et al. Global abnor-malities in lymphatic function following systemic therapy in patients with breast cancer[J]. Br J Surg, 2015, 102: 534-540. doi:  10.1002/bjs.9766
    [8] Ridner SH, Dietrich MS, Stewart BR, et al. Body mass index and breast cancer treatment-related lymphedema[J]. Support Care Cancer, 2011, 19: 853-857. doi:  10.1007/s00520-011-1089-9
    [9] Kwan ML, Darbinian J, Schmitz KH, et al. Risk factors for lymphedema in a prospective breast cancer survivorship study: the Pathways Study[J]. Arch Surg, 2010, 145: 1055-1063. doi:  10.1001/archsurg.2010.231
    [10] Pan WR. Atlasof lymphaticanatomy in the head, neck chest and limbs[M]. Beijing: People's Medical Publishing House, 2017: 176.
    [11] Bobbio P, Peracchia G, Pellegriano F. Connessionilinfatichepresternalifra le regioni mammary dei due lati[J]. Ateneo Parmense, 1962, 33: 95-109.
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  • 被引次数: 0
出版历程
  • 收稿日期:  2021-05-20
  • 录用日期:  2021-08-10
  • 网络出版日期:  2021-12-30
  • 刊出日期:  2022-03-30

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