MY Yan, CHENG Qianji, LU Yao, NING Jinling, GE Long. Explore the Applications and Challenges of Adaptive Design in Platform trial[J]. Medical Journal of Peking Union Medical College Hospital. DOI: 10.12290/xhyxzz.2023-0424
Citation: MY Yan, CHENG Qianji, LU Yao, NING Jinling, GE Long. Explore the Applications and Challenges of Adaptive Design in Platform trial[J]. Medical Journal of Peking Union Medical College Hospital. DOI: 10.12290/xhyxzz.2023-0424

Explore the Applications and Challenges of Adaptive Design in Platform trial

  • Adaptive design, with advantages such as dynamically adjusting trial plans, reducing resource waste, and improving trial efficiency, has broken through the competitive situation of new drug development and gradually met the needs of clinical research. In recent years, the use of adaptive design in platform trials as an innovative research model has added impetus to new drug development. This article briefly outlines the research progress , content and characteristics, common design types, statistical analysis, and case interpretation of adaptive design, introduces the concept, types, and applications of adaptive platform trials, in the hope to provide scientific references for further exploration of clinical trials and new drug development.
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